- A case of idiopathic thrombocytopenic purpura in pregnancy.
-
Mi Sook Kim, Ho Joon Hwangbo, Young Gi Lee, Yoon Kee Park, Sung Ho Lee
-
Yeungnam Univ J Med. 1993;10(2):512-517. Published online December 31, 1993
-
DOI: https://doi.org/10.12701/yujm.1993.10.2.512
-
-
 Abstract
 PDF
- Idiopathic thrombocytopenic purpura is an uncommon illness but most common form of thrombocytopema in pregnancy. Corticosteroids, splenectomy, immunosuppressive drugs, and immunoglobulin therapy have been recommended for manaaement. The optimal method of delivery is controversial. We have experienced a case of idiopathic thrombocytopenic purpura diagnosed previously and managed with corticosteroid and vincrstine, which was followed by pregnancy, vaginal delivery and postpiirtum splenectomy.
- Increased carboxyhemoglobin and serum iron concentration as an indicator of increased red cell turnover in preeclampsia.
-
Sang Heon Kim, Kwang Hee Lee, Mi Sook Kim, Young Gi Lee, Yoon Kee Park, Tae Hyung Lee, Sung Ho Lee
-
Yeungnam Univ J Med. 1993;10(1):68-76. Published online June 30, 1993
-
DOI: https://doi.org/10.12701/yujm.1993.10.1.68
-
-
Abstract
PDF
- Pregnancy induced hypertension is multifaceted syndrome with variable involvement of several key organ systems, so sensitive and specific laboratory tests for predicting severity and prognosis. and early diagnosis of this disease are required. Because heme catabolism results in equimolar production of carboxyhemoglobin, iron and bilirubin, a concomittant rise of these parameters would provide confirmation of increased heme catabolism. Microangiopathic hemolytic anemia may occurs in severe preeclampsia, but it is not known whether increased red cell turnover - occurs with mild preeclampsia as complication. The purpose of this study was to confirm that increased heme catabolism also occurs in patients with mild preeclampsia. The analysis of data was done on 23 cases with mild preeclampsia and 35 normal pregnant women, who were admitted to Yeungnam University Hospital from October 1992 to March 1993. The results were as follows. 1. The mean antepartum serum iron concentration was significantly higher in the group with mild preeclampsia (86.5+/-6.1 microg/dl) than in the controls (53.2+/-5.3 microg/dl). 2. The mean antepartum and postpartum carboxyhemoglobin concentrations were significantly higher in the group with mild preeclampsia (antepartum : 2.55+/-0.42 mg/dl, postpartum 1.21+/-0.4 mg/dl) than the controls (antepartum : 0.61+/-0.2 mg/dl, postpartum 0.53+/-0.2 mg/dl) 3. During postpartum, carboxyhemoglobin concentration in preeclampsia reduced significantly from antepartum level, but there was no difference between antepartum and postpartum carboxyhemoglobin concentrations among controls. 4. Bilirubin concentrations were similiar in both groups
|
E-Submission
Yeungnam University College of Medicine
